EVENT BT11 x 59122 x MIR604 x TC1507 x GA21 AND DETECTION METHODS

Plant: Maize (Zea mays)
Event: BT11 x 59122 x MIR604 x TC1507 x GA21
UI: SYN-BT011-1 x DAS-59122-7 x SYN-IR604-5 x DAS-01507-1 x MON-00021-9
Commercial name: Agrisure 3122
Modification: cry1Ab and cry1Fa2 genes (insect resistance: lepidoptera), cry34Ab1, cry35Ab1 and mcry3A genes (insect resistance: coleoptera), pat gene (herbicide tolerance: glufosinate), epsps gene (herbicide tolerance: glyphosate), pmi gene (marker: mannose isomerase)

maize plant pictureOriginal Cultivar and modification methods

The maize line Bt11 x 59122 x MIR604 x TC1507 x GA21 was obtained by conventional breeding of five genetically modified maize lines: the maize Bt11, the 59122, the MIR604, the TC1507 and the GA21.

Characteristics of the modification

The stacked maize line Bt11 x 59122 x MIR604 x TC1507 x GA21 inherited all the transgenes present in the GM parental lines: the cry1Ab and the pat genes from maize line Bt11, the Cry34Ab1, the Cry35Ab1 and the pat genes from maize line 59122, the mcry3A and the pmi genes from MIR604, the cry1F and the pat genes from maize line TC1507, and the mepsps gene from maize GA21. As a consequence, the stacked GM plant produces the Cry1Ab and Cry1F proteins active against certain lepidopteran insects, different Cry3A proteins active against Coleoptera, and the PAT and EPSPS enzymes which allow the plant to tolerate glufosinate-ammonium and glyphosate based herbicides.

Purpose of the modification

The stacked maize line Bt11 x 59122 x MIR604 x TC1507 x GA21 was developed to protect the plant from Lepidoptera and Coleoptera pest attacks, as well as to tolerate the application of glufosinate-ammonium and glyphosate based herbicides.
Documents
TitleYearAuthorJournal
GMO specific real-time PCR system, Protocol for event-specific quantitation of Bt11 in maize2004National Veterinary Institute (Norway) and INRA (France)-Read
Event-specific Method for the Quantification of Maize Line Bt11 Using Real-time PCR - Protocol2008Syngenta Seeds S.A.S.-Read
Maize Seeds Sampling and DNA Extraction Report on the Validation of a DNA Extraction Method from Maize Seeds and Grains2007Syngenta Seeds S.A.S.-Read
Detection of Recombinant DNA Segments Introduced to Genetically Modified Maize (Zea mays)2002Takeshi Matsuoka, Hideo Kuribara, Ken Takubo, Hiroshi Akiyama, Hirohito Miura, Yukihiro Goda, Yuko Kusakabe, Kenji Isshiki, Masatake Toyoda, and Akihiro HinoJ. Agric. Food Chem.Read
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CONSENSUS DOCUMENT ON THE BIOLOGY OF ZEA MAYS SUBSP. MAYS (MAIZE)2003OECDSeries on Harmonisation of Regulatory Oversight in BiotechnologyRead
COMMISSION COMMISSION DECISION of 19 May 2004 authorising the placing on the market of sweet corn from genetically modified maize line Bt11 as a novel food or novel food ingredient under Regulation (EC) No 258/97 of the European Parliament and of the Council2004CE-Read
Qualitative and quantitative detection of genetically modified maize and soy in processed foods sold commercially in Brazil by PCR-based methods 2005Ralf Greiner , Ursula Konietzny and Anna L.C.H. VillavicencioFood ControlRead
Commission Regulation (EU) No 619/2011 of 24 June 2011 laying down the methods of sampling and analysis for the official control of feed as regards presence of genetically modified material for which an authorisation procedure is pending or the authorisation of which has expired Text with EEA relevance2011European CommissionOfficial Journal L 166 , 25/06/2011 Read
Quantitative, multiplex ligation-dependent probe amplification for the determination of eight genetically modified maize events 2009Askild Lorentz Holck, Signe M. Drømtorp and Even HeirEuropean Food Research and Technology Volume 230, Number 2, 185-194, DOI: 10.1007/s00217-009-1155-4Read
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Detection of Six Genetically Modified Maize Lines Using Optical Thin-Film Biosensor Chips2010Sulan Bai et al.J. Agric. Food Chem., 2010, 58 (15), pp 8490–8494Read
COMMISSION DECISION of 24 October 2007 authorising the placing on the market of products containing, consisting of, or produced from genetically modified maize 59122 (DAS-59122-7) pursuant to Regulation (EC) No 1829/2003 of the European Parliament and of the Council2007CE-Read
TRANSGENIC PLANT EVENT DETECTION2010Van Den Bulcke et alUSPTORead
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Detection of five novel GMO maize events by qualitative, multiplex PCR and fluorescence capillary gel electrophoresis2010A. Holck, B. O. Pedersen and E. HeirEuropean Food Research and Technology Volume 231, Number 3, 475-483, DOI: 10.1007/s00217-010-1302-yRead
Read
Simple, sensitive, accurate multiplex quantitative competitive PCR with capillary electrophoresis detection for the determination of genetically modified maize 2011Askild Lorentz Holck and Brit Oppegård PedersenEuropean Food Research and Technology Volume 233, Number 6, 951-961Read
Event-specific Method for the Quantification of Maize Line MIR604 Using Real-time PCR - Protocol2007CRL_GMFF-Read
Maize Seeds Sampling and DNA Extraction Report on the Validation of a DNA Extraction Method from Maize Seeds2007CRL_GMFF-Read
COMMISSION DECISION of 3 November 2005 concerning the placing on the market, in accordance with Directive 2001/18/EC of the European Parliament and of the Council, of a maize product (Zea mays L., line 1507) genetically modified for resistance to certain lepidopteran pests and for tolerance to the herbicide glufosinate-ammonium2005--Read
COMMISSION DECISION of 3 March 2006 authorising the placing on the market of food containing, consisting of, or produced from genetically modified maize line 1507 (DAS-Ø15Ø7-1) pursuant to Regulation (EC) No 1829/2003 of the European Parliament and of the Council2006--Read
Event-specific method for the quantitation of maize line GA21 using real-time PCR - Protocol2005--Read
Event-specific Method for the Quantification of Maize Line GA21 Using Real-time PCR - Protocol2007--Read
Report on the Verification of Performance of a DNA Extraction Method for Maize Grains2007--Read
COMMISSION DECISION of 28 March 2008 repealing Decision 2006/69/EC authorising the placing on the market of foods and food ingredients produced from genetically modified Roundup Ready maize line GA21 as novel foods or novel food ingredients under Regulation (EC) No 258/97 of the European Parliament and of the Council2008CE-Read
COMMISSION DECISION of 28 March 2008 authorising the placing on the market of products containing, consisting of, or produced from genetically modified maize GA21 (MON-ØØØ21-9) pursuant to Regulation (EC) No 1829/2003 of the European Parliament and of the Council2008CE-Read


External links
 GMOMETHODS: EU Database of Reference Methods for GMO Analysis
 European Union Reference Laboratory for GM Food and Feed (EURL-GMFF)
 BCH - Living Modified Organism (LMO) Registry
 EU register of genetically modified food and feed
 GMO Detection method Database (GMDD)
 CERA - GM Crop Database
 OECD - BioTrack Product Database
 CropLife International Detection Methods

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Last update: 2017/12/11


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